Barbara Spagnolo graduated summa cum laude in Neurobiology, at University of Torino , by disserting a thesis on “Analysis of motor nervous systems and motor performance of APPPS1 mice, model for Alzheimer Disease”. Working on this subject she was involved in electrophysiological, behavioral and immunohistochemical experiments and data analysis. This included animal handling during in vivo experiments to analyze motor skills, neurosurgery (cerebellar peduncle lesions), single and multiunit electrophysiology and mouse perfusion/fixation. After a PhD in Biomolecular Nanotechnologies  focused on the application of 3D micro and nanofabrication approaches applied to life science (cancer), she worked on the development of transgenic cell lines for optogenetics. In the last four years she also developed different optrode designs for simultaneous optical control and electrophysiological readout of neural activity and tested them in vivo. In 2021 she started to work in IIT@CBN as a support Technician for the Multifunctional Neural Interfaces with Deep Brain Areas research line where she manages and performs activities and experiments related to the in vivo testing of newly developd optoelectronic devices, partecipating also in their design and fabrication. Additionally, she is responsible for the draw up of the animal use protocols, required in research activities/projects involving vertebrate animals.
Phone
			              	+39 0832 1816 251
	              			Research center
					              	CBN@UniLe
				              			Biografia
	              			All Publications
	                2025
										Mastrototaro G., Zaib H., Spagnolo B., De Vittorio M., Pisanello F., Kazemzadeh M.
										Deep learning-based Robust Raman Spectral Analysis: Overcoming Probe-Induced Artifacts with a Cascaded U-Net
										OPTOGEN 2025 - 10th International Workshop on Technologies for Optogenetics and Neurophotonics
									
										
											Poster
										
										
											Conference
										
										
									
								2025
										Spagnolo B., Petracca M., Kazemzadeh M., Abruzzese L., De Vittorio M., Lozupone E., Pisanello F.
										Label-free molecular analysis of brain thrombi by means of Raman spectroscopy
										OPTOGEN 2025 - 10th International Workshop on Technologies for Optogenetics and Neurophotonics
									
										
											Poster
										
										
											Conference
										
										
									
								2024
										Bianco M., Balena A., Pisanello M., Spagnolo B., Sabatini B.L., Pisanello F., De Vittorio M.
										Additive micro-fabrication on tapered optical fibers: integration of optical, electrical and thermal readout channels
										Optogen 2024
									
										
											Conference Paper
										
										
											Conference
										
										
									
								2024
										Mohammadiaria M., Bianco M., Balena A., Andriani M.S., Montinaro C., Spagnolo B., Pisano F., Pisanello F., De Vittorio M.
										Emerging technologies toward the integration of multiple functionalities on non-planar fiber optics-based implantable neurophotonics probes
										Neurophotonics
									
										
											Article
										
										
											Journal
										
										
									
								2024
										Mohammadiaria M., Bianco M., Balena A., Andriani M.S., Montinaro C., Spagnola B., Pisano F., Pisanello F., De Vittorio M.
										Emerging technologies toward the integration of multiple functionalities on non-planar implantable neurophotonics probes
										Neurophotonics, vol. 11
									Scientific Talks
	                2024
	                						Pisanello F., Pisano F., Balena A., Spagnolo B., Andriani M. S., Zheng D., Bianco M., Kazmadeh M., Collard L. J., Piscopo L., Montinaro C., Al Masmudi M., Tantussi F., De Angelis F., Perez T. J., Aslanoglu S., Sabatini B. L., Valiente M., De La Prida L. M., De Vittorio M.
	                						Bringing nanophotonics into the brain: multifunctional optical neural interfaces
	                						
	                					FENS Forum 2024
             
									        Conference
										2024
	                						Bianco M., Balena A., Pisano F., Pisanello M., Collard L. J., Zheng D., Kashif M. F., Andriani M. S., Piscopo L., Kazemzadeh M., Spagnolo B., Aslanoglou S., Montinaro C., Al Masmudi M., Parras T. J., Cid E., Valiente M., De La Prida L. M., Sabatini B. L., De Vittorio M., Pisanello F.
	                						Multifunctional Neural Interfaces with Multimodal Optical Fibers
	                						
	                					Optica Advanced Photonics Congress 2024
             
									        Conference
										2024
	                						Pisanello F., Pisano F., Balena A., Spagnolo B., Andriani M. S., Zheng D., Bianco M., Kazmadeh M., Collard L. J., Piscopo L., Montinaro C., Al Masmudi M., Tantussi F., De Angelis F., Perez T. J., Aslanoglu S., Sabatini B. L., Valiente M., De La Prida L. M., De Vittorio M.
	                						Neurophotonics with tapered optical fibers: from optogenetics to plasmonic neural interfaces
	                						
	                					9TH INTERNATIONAL WORKSHOP ON TECHNOLOGIES FOR OPTOGENETICS AND NEUROPHOTONICS - OPTOGEN 2024
             
									        Conference
										2024
	                						Aslanoglou S., Spagnolo B., Montinaro C., Perna A., Ribeiro J., Andriani M. S., Piscopo L., Pisanello M., Bianco M., Balena A., Berdondini L., Fellin T., Pisanello F., De Vittorio M.
	                						Optical fiber integrated functional elements fabricated by two-photon polymerization
	                						
	                					24th International Conference on Transparent Optical Networks (ICTON 2024)
             
									        Conference
										2024
	                						de Guzman A.E., Galbusera A., Spagnolo B., Pisano F., Pisanello M., Balasco L., Bozzi Y., De Vittorio M., Fellin F., Pisanello F., Gozzi A.
	                						Probing functional network dynamics with optogenetic-fMRI
	                						
	                					Multimodal brain imaging of neuronal pathways and networks in rodents, primates and humans
             
									        Workshop/Symposium
										Oral presentations
	                2021
	                						Spagnolo B., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
	                						Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
	                						MNE 2021
	                					Conference
										2021
	                						Spagnolo B., Balena A., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
	                						Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
	                						MNE
	                					Conference
										2021
	                						Spagnolo B., Sileo L., Pisanello M., Pisano F., Balena A., DeVittorio M., Pisanello F.
	                						Interfacing with small brain volumes taperedfiber-based optrode
	                						OSA: Biophotonics Congress
	                					Conference
										2021
	                						Spagnolo B., Peixoto R.T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., DeVittorio M., Pisanello F.
	                						Interfacing with small brain volumes with tapered fiber-based optrode
	                						Optics InfoBase Conference Papers
	                					Conference
										2020
	                						Spagnolo B., Pisanello M., Sileo L., Pisano F., Balena A., Pisanello F., DeVittorio M.
	                						Advanced optoelectronic devices for neuroscience
	                						ICTON 2020
	                					Conference
										Colleagues of Multifunctional Neural Interfaces with deep-brain regions